7-Amino-3-cephem-4-aside aside
Amakuru y'ibanze:
Icyongereza bita:
7-ANCA; 7-AMOCA; (6R, 7R) -7-AMino-8-oxo-5-thia-1-azabicyclo NACA、7-ANCA; 7-ANCAChemicalbookimpure;
Numero ya CAS: 36923-17-8
Inzira ya molekulari: C7H8N2O3S
Uburemere bwa molekuline: 200.21
EINECS nimero: 609-312-7
Inzira yuburyo:
Ibyiciro bifitanye isano: Abahuza kama; Abahuza imiti; Ibikoresho bya farumasi.
Ingingo yo gushonga: 215-218 ° C.
Ingingo yo guteka: 536.9 ± 50.0 ° C (Biteganijwe)
Ubucucike: 1.69 ± 0.1g / cm3 (Biteganijwe)
Igipimo cyangirika: 1.735 (igereranya)
Ingingo yerekana: 278.508 ° C.
Gukemura: Gukemuka mumazi ya acide acide (gake, ashyushye), DMSO (gake). Ibyiza: Ifu yera cyangwa yera ya kirisiti.
Umuvuduko wumwuka: 0mmHg kuri 25 ° C.
| Ibisobanuro | igice | bisanzwe |
| Kugaragara | Ifu yera cyangwa yera ifu ya kirisiti | |
| Ibirimo | % | ≥98.5% |
| Ubushuhe | % | ≤1 |
| Mono hybrid | % | ≤0.5 |
| Akajagari | % | ≤1 |
Cephalosporin, ikoreshwa nkigihe cya cefbutan na cefazoxime.
Acide yibanze ya sulfurike (104.3mL, 1.92mol) yongewemo mumacupa atatu, hanyuma aside isofthalic (40g, 0.24mol) yongerwamo, irashyushya kandi ishyuha kugeza kuri 60 ℃, ifata 0.5h, na 60% acide nitric (37.8g, 0.36) mol) yongeyeho kugenzura urwego rwihuta. Ongeraho mumasaha 2. Nyuma yo kongeramo, ubushyuhe bwo kubika ubushyuhe kuri 60 ℃ kumasaha 2. Nkonje kugeza munsi ya 50 ° C, hanyuma ongeramo 100mL y'amazi. Ibikoresho byakonjeshejwe ubushyuhe bwicyumba, bisukwa muyungurura, bipompa kugirango bikureho aside imyanda, cake yo kuyungurura yogejwe namazi, ayungurura kugirango yongere yongere, kandi ibicuruzwa byera byari garama 34,6, umusaruro wari 68.4%.
20Kg cyangwa 25Kg / indobo, indobo yamakarito, itondekanye umurongo wera hamwe n umufuka wa polyethylene wirabura. 2 ℃ -8 ℃ ahantu humye, hakonje, kure yububiko bworoshye, bwemewe kumyaka 2.
