Sulfadiazine sodium ni antibiyotike ikora ya sulfonamide ikora igira ingaruka za antibacterial kuri bagiteri nyinshi za Gram-nziza na Gram-mbi. Ifite ingaruka za antibacterial kuri non-enzyme itanga Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, Neisseria gonorrhoeae, Neisseria meningitidis, na Haemophilus grippee. Byongeye kandi, ikora kandi kurwanya Chlamydia trachomatis, Nocardia asteroide, Plasmodium, na Toxoplasma muri vitro. Ibikorwa bya antibacterial yiki gicuruzwa ni kimwe na sulfamethoxazole. Nyamara, mu myaka yashize, kurwanya bagiteri kuri iki gicuruzwa byiyongereye, cyane cyane Streptococcus, Neisseria, na Enterobacteriaceae.