C45h56N7o9p Guanasine, 5 '-Ibisini (4-uburyo bwo gukoresha-1' -ibisobanuro (1-methyyl) (ACI)

Amakuru y'ibanze:

Ohereza imeri kuri twe

Ibisobanuro birambuye

Ibicuruzwa

Ibisobanuro birambuye

Umubare wa kabiri

150780-67-9

H303

Imbaraga z'umubiri	Agaciro	Imiterere
Uburemere bwa molekile	869.94	-
PKA (byahanuwe)	9.16 ± 0.20	Acide menshi: 25 ° C.

Andi mazina n'ibiranga

N # CCCOP (OC1C (OC (OC (NC = 3c (= o) n = cc) cc (cc = cc = cc (c (c (c (c (c (c (c (c (c) c (c) c

Isomenic kumwenyura

C C = C4) (C5 = CC = C (OC) C = C5) C6 = CC = CC = CC = CA = CL

Inchi

InChI= 1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-

46) 52 (29) 4) 4) 30 (5) 6) 36 (60-43) (31-14-16-30 (56-32-30 (56-5-35 (56-8) 23-19-33 / H10-13,27 -30

Inchi

Irrdhrzuoznwdj-Mlldkzsosa-n

1 irindi zina ryibi bintu

Guanosine, 5 '-O- [Bis (4-Uburyo bwa Ocfaxypyl) phenylmethyl] -2 '-O-Urugo-N- (2-methyl-1-Oxopropyl) -, 3 '- [2-Cyanoethyl Bis (1-meskhotyl) fosiphoramidite] (9Ci)

Imyitozo ngororamubiri

Spectra irahari
13 c nmr
Hetero nmr

Ibiranga byahanuwe

Ibyiza birahari
Ibinyabuzima
Imiti
Lipinski
Imiterere

Ibinyabuzima

Umutungo	Agaciro	Imiterere	Isoko
BioConcentration	183	ph 1; Temp: 25 ° C.	(1) acd
BioConcentration	3890	ph 2; Temp: 25 ° C.	(1) acd
BioConcentration	35500	ph 3; Temp: 25 ° C.	(1) acd
BioConcentration	1.08 x 105	ph 4; Temp: 25 ° C.	(1) acd
BioConcentration	1.36 x 105	ph 5; Temp: 25 ° C.	(1) acd
BioConcentration	1.39 x 105	pH 6; Temp: 25 ° C.	(1) acd
BioConcentration	1.38 x 105	pH 7; Temp: 25 ° C.	(1) acd
BioConcentration	1.24 x 105	ph 8; Temp: 25 ° C.	(1) acd
BioConcentration	63600	pH 9; Temp: 25 ° C.	(1) acd
BioConcentration	11900	PH 10; Temp: 25 ° C.	(1) acd

Imiti

Umutungo	Agaciro	Imiterere	Isoko
Koc	220	ph 1; Temp: 25 ° C.	(1) acd
Koc	4680	ph 2; Temp: 25 ° C.	(1) acd
Koc	42600	ph 3; Temp: 25 ° C.	(1) acd
Koc	1.30 x 105	ph 4; Temp: 25 ° C.	(1) acd
Koc	1.63 x 105	ph 5; Temp: 25 ° C.	(1) acd
Koc	1.67 x 105	pH 6; Temp: 25 ° C.	(1) acd
Koc	1.65 x 105	pH 7; Temp: 25 ° C.	(1) acd
Koc	1.49 x 105	ph 8; Temp: 25 ° C.	(1) acd

Umutungo	Agaciro	Imiterere	Isoko
Koc	76400	pH 9; Temp: 25 ° C.	(1) acd
Koc	14200	PH 10; Temp: 25 ° C.	(1) acd
Logd	4.19	ph 1; Temp: 25 ° C.	(1) acd
Logd	5.52	ph 2; Temp: 25 ° C.	(1) acd
Logd	6.48	ph 3; Temp: 25 ° C.	(1) acd
Logd	6.96	ph 4; Temp: 25 ° C.	(1) acd
Logd	7.06	ph 5; Temp: 25 ° C.	(1) acd
Logd	7.07	pH 6; Temp: 25 ° C.	(1) acd
Logd	7.07	pH 7; Temp: 25 ° C.	(1) acd
Logd	7.02	ph 8; Temp: 25 ° C.	(1) acd
Logd	6.73	pH 9; Temp: 25 ° C.	(1) acd
Logd	6.00	PH 10; Temp: 25 ° C.	(1) acd
LogP	7.072 ± 0.721	Temp: 25 ° C.	(1) acd
Misa yimbere	1.2 x 10-4 g / l	Temp: 25 ° C.	(1) acd
Rusange	0.096 G / L.	ph 1; Temp: 25 ° C.	(1) acd
Rusange	4.3 x 10-3 G / L.	ph 2; Temp: 25 ° C.	(1) acd
Rusange	4.8 x 10-4 g / l	ph 3; Temp: 25 ° C.	(1) acd
Rusange	1.6 x 10-4 g / l	ph 4; Temp: 25 ° C.	(1) acd
Rusange	1.2 x 10-4 g / l	ph 5; Temp: 25 ° C.	(1) acd
Rusange	1.2 x 10-4 g / l	pH 6; Temp: 25 ° C.	(1) acd
Rusange	1.2 x 10-4 g / l	pH 7; Temp: 25 ° C.	(1) acd
Rusange	1.4 x 10-4 g / l	ph 8; Temp: 25 ° C.	(1) acd
Rusange	2.7 x 10-4 g / l	pH 9; Temp: 25 ° C.	(1) acd
Rusange	1.4 x 10-3 G / L.	PH 10; Temp: 25 ° C.	(1) acd
Rusange	1.2 x 10-4 g / l	Amazi atagenzuwe PH 7.00; Temp: 25 ° C.	(1) acd
Morlar Mainsic Lowelity	1.4 x 10-7 mol / l	Temp: 25 ° C.	(1) acd
Umuryango wawe	1.1 x 10-4 Mol / l	ph 1; Temp: 25 ° C.	(1) acd
Umuryango wawe	5.0 x 10-6 Mol / l	ph 2; Temp: 25 ° C.	(1) acd
Umuryango wawe	5.5 x 10-7 mol / l	ph 3; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.8 x 10-7 mol / l	ph 4; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.4 x 10-7 mol / l	ph 5; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.4 x 10-7 mol / l	pH 6; Temp: 25 ° C.	(1) acd

Umutungo	Agaciro	Imiterere	Isoko
Umuryango wawe	1.4 x 10-7 mol / l	pH 7; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.6 x 10-7 mol / l	ph 8; Temp: 25 ° C.	(1) acd
Umuryango wawe	3.1 x 10-7 mol / l	pH 9; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.6 x 10-6 mol / l	PH 10; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.4 x 10-7 mol / l	Amazi atagenzuwe PH 7.00; Temp: 25 ° C.	(1) acd
Uburemere bwa molekile	869.94
PKA	9.16 ± 0.20	Acide menshi: 25 ° C.	(1) acd
PKA	3.45 ± 0.70	Icyiciro cyibanze: 25 ° C.	(1) acd

Lipinski

Umutungo	Agaciro	Imiterere	Isoko
Ubusambanyi bwuzuye	19		(1) acd
H yemera	16		(1) acd
H	2		(1) acd
H umuterankunga / kubyemera	18		(1) acd
LogP	7.072 ± 0.721	Temp: 25 ° C.	(1) acd
Uburemere bwa molekile	869.94