C50h60N5o10p Cytidine, N-Benzoyl-5 '-Igisimba (4-N-BIS (1-ya Methyylyl) - 1-Ibisinzirathyl) (ACI)

Amakuru y'ibanze:

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Ibicuruzwa

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Umubare wa kabiri

163759-94-2

Imbaraga z'umubiri	Agaciro	Imiterere
Uburemere bwa molekile	922.01	-
PKA (byahanuwe)	8.59 ± 0.40	Acide menshi: 25 ° C.

Andi mazina n'ibiranga

Inseko ya kanonical

N #

Isomenic kumwenyura

C (OC [C @@ H] 1 [C @@ (N (C (CC) N = CC (CC = CC = CC) = C2) (C2 = CC = C (oc) c = c4) (C5 = cc = c (oc) c = c5) c6 = cc = cc = cc = cc = cc = cc = cc = cc = cc = cc = cc = cc = c

Inchi

Inchi = 1S / C50h60NO10P / C1-34 (2) 55 (35 (35-44-5-50 (3-9-13,39-38,3-7) (59-7) (59-7) (59-7) 25-21-39 ) 40-22-2622 (60-3-40) 64-48 (45 (44) 61-30-6) 57) 57 (56) 57-16-12,16,36,34- 35,43-45,48h, 15,29-31,33h2,13-8h3, (h, 52,53,56,56.57) / t43-, 48-, 66? / M1 / s1

Inchi

Flidvmliidvdsn-GicdFoiu-n

26 Andi mazina yibi bintu

Cytidine,N-Benzoyl-5 '-O- [Bis (4-Uburyo bwa Ocfaxypyl) phenylmethyl] -2 '-O-. 12: Pn: Wo03084478 Page: 57 yasabye ADN; 14: Pn: Us20030170636 Urupapuro: 17 yasabye ADN; 15: Pn: u

S20030211606 page: 19 yasabye ADN; 15: Pn: Us20030212017 page: 19 yasabye ADN; 16: Pn: Us20040005569 Page: 22 yasabye ADN; 17: Pn: US20040006030 page: 23 yasabye ADN; 17: Pn: Us20040014049 Page: 20 yasabye ADN; 18: Pn: US20040014047 Pag E: 20 yasabye ADN; 18: Pn: Us20040014048 Page: 20 yasabye ADN; 18: Pn: Us2004001400 Page: 20 yasabye ADN; 19: Pn: u

S20030171313 Page: 9 yasabye ADN; 19: Pn: Us20030198965 Page: 20 yasabye ADN; 19: Pn: Us20040005565 page: 17-16 yasabye ADN; 19: Pn: US20040005570 page: 20 yasabye ADN; 19: Pn: Us2004001405 Page: 22 yasabye ADN; 20: Pn: US20040014699 Pag

E: 20 yasabye ADN; 21: Pn: Us20040006029 Page: 23 yasabye ADN; 21: Pn: Won3106645 Page: 72 yasabye ADN; 61: Pn: US20030

166592 Page: 15 yasabye ADN; 7: Pn: Wo2005006958 Page: 62 yasabye ADN; 84: Pn: Us20040171566 page: 18 yasabye ADN; 92:

Pn: US20040005707 Page: 20 yasabye ADN; 9: Pn: wo2005007825 page: 62 yasabye ADN;N4-Benzoyl-2 '-O-Kabahotythyyl-5-O- Dimethoxytrityl-5-MethycyTitine-3 '-Phospiphelite;N4-Benzoyl-2 '-O-Karishathyl-5 '-O-ibikoresho-5-methylcytidine-3 '- AMITITE

Imyitozo ngororamubiri

Spectra irahari
13 c nmr
Hetero nmr

Ibiranga byahanuwe

Ibyiza birahari
Ibinyabuzima
Imiti
Lipinski
Imiterere

Ibinyabuzima

Umutungo	Agaciro	Imiterere	Isoko
BioConcentration	171	ph 1; Temp: 25 ° C.	(1) acd
BioConcentration	1250	ph 2; Temp: 25 ° C.	(1) acd
BioConcentration	47600	ph 3; Temp: 25 ° C.	(1) acd
BioConcentration	6.44 x 105	ph 4; Temp: 25 ° C.	(1) acd
BioConcentration	1.00 x 106	ph 5; Temp: 25 ° C.	(1) acd
BioConcentration	1.00 x 106	pH 6; Temp: 25 ° C.	(1) acd
BioConcentration	1.00 x 106	pH 7; Temp: 25 ° C.	(1) acd
BioConcentration	7.79 x 105	ph 8; Temp: 25 ° C.	(1) acd
BioConcentration	1.63 x 105	pH 9; Temp: 25 ° C.	(1) acd
BioConcentration	30800	PH 10; Temp: 25 ° C.	(1) acd

Imiti

Umutungo	Agaciro	Imiterere	Isoko
Koc	106	ph 1; Temp: 25 ° C.	(1) acd
Koc	773	ph 2; Temp: 25 ° C.	(1) acd
Koc	29500	ph 3; Temp: 25 ° C.	(1) acd

Umutungo	Agaciro	Imiterere	Isoko
Koc	3.99 x 105	ph 4; Temp: 25 ° C.	(1) acd
Koc	8.02 x 105	ph 5; Temp: 25 ° C.	(1) acd
Koc	8.70 x 105	pH 6; Temp: 25 ° C.	(1) acd
Koc	8.16 x 105	pH 7; Temp: 25 ° C.	(1) acd
Koc	4.83 x 105	ph 8; Temp: 25 ° C.	(1) acd
Koc	1.01 x 105	pH 9; Temp: 25 ° C.	(1) acd
Koc	19100	PH 10; Temp: 25 ° C.	(1) acd
Logd	4.48	ph 1; Temp: 25 ° C.	(1) acd
Logd	5.34	ph 2; Temp: 25 ° C.	(1) acd
Logd	6.92	ph 3; Temp: 25 ° C.	(1) acd
Logd	8.06	ph 4; Temp: 25 ° C.	(1) acd
Logd	8.36	ph 5; Temp: 25 ° C.	(1) acd
Logd	8.39	pH 6; Temp: 25 ° C.	(1) acd
Logd	8.37	pH 7; Temp: 25 ° C.	(1) acd
Logd	8.14	ph 8; Temp: 25 ° C.	(1) acd
Logd	7.46	pH 9; Temp: 25 ° C.	(1) acd
Logd	6.73	PH 10; Temp: 25 ° C.	(1) acd
LogP	8.401 ± 0.723	Temp: 25 ° C.	(1) acd
Misa yimbere	1.4 x 10-4 g / l	Temp: 25 ° C.	(1) acd
Rusange	1.1 g / l	ph 1; Temp: 25 ° C.	(1) acd
Rusange	0.16 g / l	ph 2; Temp: 25 ° C.	(1) acd
Rusange	4.1 x 10-3 G / L.	ph 3; Temp: 25 ° C.	(1) acd
Rusange	3.0 x 10-4 g / l	ph 4; Temp: 25 ° C.	(1) acd
Rusange	1.5 x 10-4 g / l	ph 5; Temp: 25 ° C.	(1) acd
Rusange	1.4 x 10-4 g / l	pH 6; Temp: 25 ° C.	(1) acd
Rusange	1.5 x 10-4 g / l	pH 7; Temp: 25 ° C.	(1) acd
Rusange	2.5 x 10-4 g / l	ph 8; Temp: 25 ° C.	(1) acd
Rusange	1.2 x 10-3 G / L.	pH 9; Temp: 25 ° C.	(1) acd
Rusange	6.3 x 10-3 G / L.	PH 10; Temp: 25 ° C.	(1) acd
Rusange	1.5 x 10-4 g / l	Itanu y'amazi ya ph 6.97; Temp: 25 ° C.	(1) acd
Morlar Mainsic Lowelity	1.5 x 10-7 mol / l	Temp: 25 ° C.	(1) acd
Umuryango wawe	1.2 x 10-3 mol / l	ph 1; Temp: 25 ° C.	(1) acd

Umutungo	Agaciro	Imiterere	Isoko
Umuryango wawe	1.7 x 10-4 Mol / l	ph 2; Temp: 25 ° C.	(1) acd
Umuryango wawe	4.4 x 10-6 mol / l	ph 3; Temp: 25 ° C.	(1) acd
Umuryango wawe	3.2 x 10-7 mol / l	ph 4; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.6 x 10-7 mol / l	ph 5; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.5 x 10-7 mol / l	pH 6; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.6 x 10-7 mol / l	pH 7; Temp: 25 ° C.	(1) acd
Umuryango wawe	2.7 x 10-7 mol / l	ph 8; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.3 x 10-6 Mol / l	pH 9; Temp: 25 ° C.	(1) acd
Umuryango wawe	6.8 x 10-6 Mol / l	PH 10; Temp: 25 ° C.	(1) acd
Umuryango wawe	1.6 x 10-7 mol / l	Itanu y'amazi ya ph 6.97; Temp: 25 ° C.	(1) acd
Uburemere bwa molekile	922.01
PKA	8.59 ± 0.40	Acide menshi: 25 ° C.	(1) acd
PKA	3.87 ± 0.20	Icyiciro cyibanze: 25 ° C.	(1) acd

Lipinski

Umutungo	Agaciro	Imiterere	Isoko
Ubusambanyi bwuzuye	22		(1) acd
H yemera	15		(1) acd
H	1		(1) acd
H umuterankunga / kubyemera	16		(1) acd
LogP	8.401 ± 0.723	Temp: 25 ° C.	(1) acd
Uburemere bwa molekile	922.01