Methyl 2,2-difluorobenzo [d]

Methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-karubasini imiti ivanze na molekuline ya C9H6F2O4 na CAS nimero 773873-95-3. Bizwi kandi na synonyme nyinshi, nka methyl 2,2-difluoro-1,3-benzodioxole-5-carboxylate, 2,2-difluorobenzodioxole-5-karubasi ya acide methyl ester, na EOS-61003. Nibice byurwego rwa heterocyclic hamwe na ogisijeni hetero-atom gusa.

Kurata ubuziranenge bwa 98% byibuze, iyi nteruro yo mu rwego rwa farumasi nigisubizo kinyuranye ku nganda nka farumasi, imiti y’ubuhinzi, n’ubushakashatsi. Uru ruganda rukoreshwa nkurwego rwibanze mu guhuza imiti, gukora ibicuruzwa birinda ibihingwa, n’ubushakashatsi bwa siyansi.

Muri iki kiganiro, tuzasobanura imiterere irambuye yibicuruzwa n'imikorere ya methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate, dushingiye ku makuru aboneka.

Ibintu bifatika na shimi

Methyl 2,2-difluorobenzo [d] Ifite uburemere bwa 216.14 g / mol n'ubucucike bwa 1.5 ± 0.1 g / cm3. Ifite aho itetse ya 227.4 ± 40.0 ° C kuri 760 mmHg hamwe na flash ya 88.9 ± 22.2 ° C. Ifite umuvuduko muke wa 0.1 ± 0.4 mmHg kuri 25 ° C hamwe n’amazi make ya 0.31 g / L kuri 25 ° C. Ifite ibiti P bifite agaciro ka 3.43, byerekana ko ikemuka cyane mumashanyarazi kama kuruta mumazi.

Imiterere ya methyl 2,2-difluorobenzo [d] . Kubaho kwa atome ya fluor byongera ituze hamwe nubusembwa bwikigo, kimwe na lipofilicity na bioavailability. Itsinda rya Carboxylate rirashobora gukora nkitsinda risiga cyangwa nucleophile mubitekerezo bitandukanye. Impeta ya 1,3-dioxyde irashobora gukora nka glycol yuzuye mask cyangwa dienophile mubitekerezo bya cycloaddition.

Umutekano no Gukemura

Methyl 2,2-difluorobenzo [d] Ifite ibyatangajwe bikurikira nibisobanuro byo kwirinda:

• H315: Bitera kurwara uruhu

• H319: Bitera uburakari bukabije bw'amaso

• H335: Birashobora gutera uburakari

• P261: Irinde guhumeka umukungugu / fume / gaze / igihu / imyuka / spray

• P305 + P351 + P338: NIBA MU MASO: Koza neza witonze n'amazi muminota mike. Kuraho lenses zo guhuza, niba zihari kandi byoroshye gukora. Komeza kwoza

• P302 + P352: NIBA KUBURWA: Koza n'isabune nyinshi n'amazi

Ingamba zambere zubutabazi kuri methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate niyi ikurikira:

• Guhumeka: Niba ushizemo umwuka, shyira umurwayi umwuka mwiza. Niba guhumeka bigoye, tanga ogisijeni. Niba udahumeka, tanga guhumeka. Witondere ubuvuzi

• Guhuza uruhu: Kuraho imyenda yanduye kandi koza uruhu neza ukoresheje isabune n'amazi. Niba wumva bitagushimishije, shaka ubuvuzi

• Guhuza amaso: Tandukanya ijisho hanyuma ukarabe n'amazi atemba cyangwa saline isanzwe. Shakisha ubuvuzi bwihuse

• Kwinjiza: Gargle, ntutere kuruka. Shakisha ubuvuzi bwihuse

Ingamba zo gukingira umuriro kuri methyl 2,2-difluorobenzo [d] [1,3] dioxole-5-carboxylate niyi ikurikira:

• Kuzimya ibikoresho: Kuzimya umuriro hamwe nigicu cyamazi, ifu yumye, ifuro cyangwa karuboni ya dioxyde de carbone. Irinde gukoresha amazi atemba kugirango uzimye umuriro, ushobora gutera kumeneka amazi yaka kandi ugakwirakwiza umuriro

• Ibyago bidasanzwe: Nta makuru ahari

• Kwirinda umuriro ningamba zo gukingira: Abashinzwe kuzimya umuriro bagomba kwambara ibikoresho bihumeka ikirere, bakambara imyenda yuzuye yumuriro, kandi bakarwanya umuriro. Niba bishoboka, wimure kontineri mumuriro ujye ahantu hafunguye. Ibikoresho biri mu muriro bigomba guhita bimurwa iyo bihindutse ibara cyangwa bisohora amajwi bivuye mu bikoresho by’ubutabazi. Tandukanya ahabereye impanuka kandi ubuze abakozi badafite aho bahurira. Harimo kandi utunganyirize amazi yumuriro kugirango wirinde kwanduza ibidukikije

Umwanzuro

Methyl 2,2-difluorobenzo [d] Ifite imiterere idasanzwe hamwe na atome ebyiri za fluor hamwe nitsinda rya karubasi yometse kumpeta ya benzodioxole, itanga ituze, reaction, lipophilicity, na bioavailable kuri compound. Ifite amazi make hamwe nubushyuhe bwumuyaga, hamwe nubushyuhe buringaniye hamwe na flash point. Byashyizwe mubintu byangiza kandi bisaba gufata neza no kubika. Ifite ibisabwa mubikorwa bitandukanye, nka farumasi, ubuhinzi-mwimerere, ubushakashatsi, nibindi.

Kubindi bisobanuro cyangwa ibibazo, nyamunekatwandikire:

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