Praziquantel

ibicuruzwa

Praziquantel

Amakuru y'ibanze:

Praziquantel ni ifumbire mvaruganda hamwe na formula ya chimique C 19 H 24 N 2 O 2. Ni anthelmintique ikoreshwa mubantu ninyamaswa. Irakoreshwa byumwihariko kuvura tapeworms na flukes. Ifite akamaro kanini kurwanya schistosoma japonicum, umwijima wo mu Bushinwa, na latum ya Diphyllobothrium.

Imiti yimiti: C 19 H 24 N 2 O 2

Uburemere bwa molekuline: 312.406

CAS No.: 55268-74-1

EINECS nimero: 259-559-6


Ibicuruzwa birambuye

Ibicuruzwa

Umutungo wa fiziki

Ubucucike: 1,22 g / cm3
Ingingo yo gushonga: 136-142 ° C.
Ingingo yo guteka: 544.1 ° C.
Ingingo yerekana: 254,6 ° C.
Igipimo cyangirika: 1.615
Kugaragara: Ifu yera cyangwa yera-ifu ya kristaline

Koresha

Ikoreshwa cyane cyane nk'umuti mugari wa antiparasitike mugukiza no gukumira schistosomiasis, cysticercose, paragonimiasis, echinococcose, fasciococcus, echinococcose, na virusi ya helminth.

Ibiranga

Ibicuruzwa byera cyangwa byera-ifu ya kristaline.
Ibicuruzwa byoroshye gushonga muri chloroform, gushonga muri Ethanol, no kudashonga muri ether cyangwa mumazi.

Ingingo yo gushonga

Ingingo yo gushonga yibicuruzwa (Amategeko rusange 0612) ni 136 ~ 141 ℃.

icyiciro

Anthelmintics.

Ibyerekana

Numuti mugari urwanya trematode na tapeworms. Irakwiriye kuri schistosomiya zitandukanye, clonorchiasis, paragonimiasis, fasciolose, indwara ya tapeworm na cysticercose.

Igikorwa cya farumasi

Iki gicuruzwa ahanini gitera ubumuga bwa spastique no kumena schistosomes na tapeworms mubakira binyuze mu ngaruka zisa na 5-HT. Ifite ingaruka nziza kubantu benshi bakuze kandi badakuze. Muri icyo gihe, irashobora kugira ingaruka kuri calcium ion ya calcium mu ngirangingo z'imitsi y'umubiri w'inyo, ikongera iyinjira rya calcium ion, ikabuza kongera gufata pompe ya calcium ya sarcoplasmic reticulum, byongera cyane intungamubiri za calcium mu ngirangingo z'imitsi y'inzoka. umubiri, kandi utera umubiri winyo kumugara no kugwa.

Ububiko

Irinde urumuri kandi ubike mu kintu gifunze.


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