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118 Re36H44N2O8Si Uridine, 5′-O-

ibicuruzwa

118 Re36H44N2O8Si Uridine, 5′-O-
  • 118 Re36H44N2O8Si Uridine, 5′-O-

118 Re36H44N2O8Si Uridine, 5′-O-

Amakuru y'ibanze:


Ibicuruzwa birambuye

Ibicuruzwa

Imiterere yumubiri

Ibyingenzi Byumubiri Agaciro Imiterere
Uburemere bwa molekile 660.83 -
Ubucucike (Biteganijwe) 1.24 ± 0.1 g / cm3 Ubushyuhe: 20 ° C;Kanda: 760 Torr
pKa (Byahanuwe) 9.39 ± 0.10 Ubushyuhe bwinshi bwa Acide: 25 ° C.

Andi mazina nibiranga

Urwenya rwa Canonical O = C1C = CN (C (= O) N1) C2OC (COC (C = 3C = CC = CC3) (C4 = CC = C (OC) C = C4) C5 = CC = C (OC) C = C5) C (O) C2O [Si] (C) (C) C (C) (C) C.
Isomeric SMILES
C (OC [C @ H] 1O [C @ H] ([C @ H] (O [Si] (C (C) (C) C) (C) C) [C @@ H] 1O) N2C ( = O) NC (= O) C = C2) (C3 = CC = C (OC) C = C3) (C4 = CC = C (OC) C = C4) C5 = CC = CC = C5
InChI
InChI = 1S / C36H44N2O8Si / c1-35 (2,3) 47 (6,7) 46-32-31 (40) 29 (45-33 (32) 38-22-21-30 (39) 37-34 ( 38) 41) 23-44-36 (24-11-9-8-10-12-24,25-13- 17-27 (42-4) 18-14-25) 26-15-19-28 ( 43-5) 20-16-26 / h8-22,29,31-33,40H, 23H2,1-7H3, (H, 37,39,41) / t29-, 31-, 32-, 33- / m1 / s1
InChI Urufunguzo
KVHQIELPHWJPSY-WXQJYUTRSA-N
2 Andi mazina kuriyi ngingo
5′-O- [Bis (4-mikorerexyphenyl) fenylmethyl] -2′-O -2′-O-tert-Butyldimethylsilyl-5′-O- (4,4′- dimethoxytrityl) uridine

Ikigereranyo

Spectra irahari
1H NMR
13C NMR
Hetero NMR
Misa

Ibintu Byateganijwe

Ibyiza birahari
Ibinyabuzima
Imiti
Ubucucike
Lipinski
Imiterere ijyanye

Ibinyabuzima

Umutungo Agaciro Imiterere Inkomoko
Ikintu cya Bioconcentration 2.21 x 105 pH 1;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.21 x 105 pH 2;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.21 x 105 pH 3;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.21 x 105 pH 4;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.21 x 105 pH 5;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.21 x 105 pH 6;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.20 x 105 pH 7;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 2.12 x 105 pH 8;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 1.54 x 105 pH 9;Ubushyuhe: 25 ° C. (1) ACD
Ikintu cya Bioconcentration 42500 pH 10;Ubushyuhe: 25 ° C. (1) ACD

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Imiti

Umutungo Agaciro Imiterere Inkomoko
Koc 2.33 x 105 pH 1;Ubushyuhe: 25 ° C. (1) ACD
Koc 2.33 x 105 pH 2;Ubushyuhe: 25 ° C. (1) ACD
Koc 2.33 x 105 pH 3;Ubushyuhe: 25 ° C. (1) ACD
Koc 2.33 x 105 pH 4;Ubushyuhe: 25 ° C. (1) ACD
Koc 2.33 x 105 pH 5;Ubushyuhe: 25 ° C. (1) ACD
Koc 2.33 x 105 pH 6;Ubushyuhe: 25 ° C. (1) ACD

 

Umutungo Agaciro Imiterere Inkomoko
Koc 2.32 x 105 pH 7;Ubushyuhe: 25 ° C. (1) ACD
Koc 2.23 x 105 pH 8;Ubushyuhe: 25 ° C. (1) ACD
Koc 1.62 x 105 pH 9;Ubushyuhe: 25 ° C. (1) ACD
Koc 44800 pH 10;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 1;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 2;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 3;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 4;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 5;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 6;Ubushyuhe: 25 ° C. (1) ACD
logD 7.33 pH 7;Ubushyuhe: 25 ° C. (1) ACD
logD 7.32 pH 8;Ubushyuhe: 25 ° C. (1) ACD
logD 7.18 pH 9;Ubushyuhe: 25 ° C. (1) ACD
logD 6.62 pH 10;Ubushyuhe: 25 ° C. (1) ACD
logP 7.334 ± 0.643 Ubushyuhe: 25 ° C. (1) ACD
Mass Massins Solubility 3.5 x 10-5 g / L. Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 1;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 2;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 3;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 4;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 5;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 6;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. pH 7;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.6 x 10-5 g / L. pH 8;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 5.0 x 10-5 g / L. pH 9;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 1.9 x 10-4 g / L. pH 10;Ubushyuhe: 25 ° C. (1) ACD
Gukemura ibibazo 3.5 x 10-5 g / L. Amazi adafite amazi pH 7.00;Ubushyuhe: 25 ° C. (1) ACD
Molar Intrinsic Solubility 5.3 x 10-8 mol / L. Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. pH 1;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. pH 2;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. pH 3;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. pH 4;Ubushyuhe: 25 ° C. (1) ACD

 

Umutungo Agaciro Imiterere Inkomoko
Amashanyarazi 5.3 x 10-8 mol / L. pH 5;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. pH 6;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. pH 7;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.5 x 10-8 mol / L. pH 8;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 7.6 x 10-8 mol / L. pH 9;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 2.8 x 10-7 mol / L. pH 10;Ubushyuhe: 25 ° C. (1) ACD
Amashanyarazi 5.3 x 10-8 mol / L. Amazi adafite amazi pH 7.00;Ubushyuhe: 25 ° C. (1) ACD
Uburemere bwa molekile 660.83    
pKa 9.39 ± 0.10 Ubushyuhe bwinshi bwa Acide: 25 ° C. (1) ACD

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Ubucucike

Umutungo Agaciro Imiterere Inkomoko
Ubucucike 1.24 ± 0.1 g / cm3 Ubushyuhe: 20 ° C;Kanda: 760 Torr (1) ACD
Umubumbe wa Molar 528.8 ± 5.0 cm3 / mol Ubushyuhe: 20 ° C;Kanda: 760 Torr (1) ACD

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Lipinski

Umutungo Agaciro Imiterere Inkomoko
Impapuro zishobora guhinduka 13   (1) ACD
H Abakira 10   (1) ACD
H Abaterankunga 2   (1) ACD
H Abaterankunga / Abemera Sum 12   (1) ACD
logP 7.334 ± 0.643 Ubushyuhe: 25 ° C. (1) ACD
Uburemere bwa molekile 660.83    

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Imiterere ijyanye

Umutungo Agaciro

Imiterere

 Inkomoko
Ubuso bwa polarike 116 A2 (1) ACD

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Ibiteganijwe

Spectra irahari
1H NMR
13C NMR

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